The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery

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The pharmacokinetics of cefazolin in patients undergoing elective & semi-elective abdominal aortic aneurysm open repair surgery

BACKGROUND Surgical site infections are common, so effective antibiotic concentrations at the sites of infection are required. Surgery can lead to physiological changes influencing the pharmacokinetics of antibiotics. The aim of the study is to evaluate contemporary peri-operative prophylactic dosing of cefazolin by determining plasma and subcutaneous interstitial fluid concentrations in patien...

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Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery.

Surgical site infections are common, so effective antibiotic concentrations at the sites of infection, i.e., in the interstitial fluid (ISF), are required. The aim of this study was to evaluate contemporary perioperative prophylactic dosing of cefazolin by determining plasma and subcutaneous ISF concentrations in patients undergoing elective/semielective abdominal aortic aneurysm (AAA) open rep...

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Evaluation of blood products utilization in abdominal aortic aneurysm repair patients’ elective surgery in ShohadaTajrish Hospital

 Abstract Background and Objectives Aortic aneurysm repair surgery (AAAs) is associated with massive bleeding that causes coagulation disorders during and after surgery. Considering that blood consumption in these patients has been studied in a few articles, we decided to investigate more. Materials and Methods In a cross-sectional study, patients with abdominal aortic aneurysms requiring surg...

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complications of elective abdominal aortic aneurysm surgery

because of significant reduction of rupture rate and increase in the patient’s life expectancy, elective surgical treatment in patients with abdominal aortic aneurysm has been widely accepted. the present article aims at assessing the postoperative complications and mortality rate in patients who had been submitted to elective surgery for abdominal aortic aneurysms. this is a retrospective stud...

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Elective open abdominal aortic aneurysm repair: a seven-year experience

INTRODUCTION The seven-year experience of elective abdominal aortic aneurysm (AAA) repair of a vascular surgical unit in a teaching hospital was reviewed to determine the factors associated with in-hospital mortality. METHODS All patients who underwent elective open repair of an AAA between July 1, 1991, and June 30, 1998, were identified using International Classification of Diseases Ninth R...

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ژورنال

عنوان ژورنال: BMC Anesthesiology

سال: 2011

ISSN: 1471-2253

DOI: 10.1186/1471-2253-11-5